The notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms.Notch is present in all metazoans, and mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region.
Posts about Notch
    • Mojang Officially Part of Microsoft, $2.5 Billion Buyout Completed

      Mojang and its hit franchise, Minecraft, now belong to Microsoft as the previously announced $2.5 billion buyout was officially completed last week. Phil Spencer, Head of Xbox, was pleased to announce the news on Twitter, stating: It’s official, today we welcome Mojang to the Microsoft Studios family. We’re excited for the possibilities ahead w/the Minecraft community.

      Zarmena Khan/ PlayStation LifeStyle- 6 readers -
  • Minecraft in 2014: Your Guide To Mods and Modpacks

    … of just a few years ago. The PC version of the game today is less about building a dirt shed to cower in overnight, and more about space exploration, magical dueling or building enormous factories controlled by banks of computers and powered by nuclear reactors. Minecraft’s ongoing popularity is largely thanks to its mods, and more recently…

    Rock, Paper, Shotgun- 5 readers -
  • Conan O’Brien On How Minecraft Celebrate Microsoft Acquisition

    … imagined just how resident Minecraftian Steve would celebrate the takeover, lavishly with nothing too expensive. Check out the video for yourself below: Minecraft creator Markus “Notch” Persson has decided to leave the franchise following many years keeping things in working order, he announced his exit through an emotional letter to fans which you…

    LzyGmrs- 2 readers -

  • Minecraft Creator Notch Takes On The Ice Bucket Challenge

    …If you’ve been on social media the last few weeks then you may have noticed celebrities dowsing themselves with buckets of ice water to raise awareness for ALS, also known as Lou Gehrig’s disease. The Ice Bucket Challenge has also made its way through the many personalities of the gaming industry and Minecraft creator Markus “Notch” Persson…

    LzyGmrs- 6 readers -
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